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By Meyyappan M.

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0 -1mA -5V 0 +5V HP analyzer Current Sensing AFM Four-probe station And HP parameter analyzer Chemical Functionalization C O 2H i-Pr2N Et - CO 2 DM F Cy N C N Cy O HO N O O H 2N Fc O O O N HN Fc O Fc = Highly selective reaction of primary amine with surface –COOH group Fe Functionalization of DNA C H 3 C lH N + CH3 CH3 N CH3 C N C lN+ H CH 3 ED C O C O 2H N C O O SO 3N a Cy3 image HN H 2N NH CH3 HO N O C O Sulfo-N H S A TG C C TTC C y3 O D N A probe O SO 3N a O N A TG C C TTC C y3 O TA C G G A A G G G G G G G G G G C y5 TargetD N A O HN Cy5 image TA C G G A A G G G G G G G G G G C y5 A TG C C TTC C y3 CNT DNA Sensor Using Electrochemical Detection 2+ 2+ 3+ 3+ e ‰ MWNT array electrode functionalized with DNA/PNA probe as an ultrasensitive sensor for detecting the hybridization of target DNA/RNA from the sample.

Extremophile Proteins for Nano-scale Substrate Patterning Nano-scale engineering for high resolution lithography Future: Bio-based lithography •Batch self-assembly •Evolving •Inexpensive “quantum dots” nm resolution The Concept • • • • Nanopore in membrane (~2nm diameter) DNA in buffer Voltage clamp Measure current G. Church, Branton D. , J. Golovchenko , Harvard D. Deamer, UC Santa Cruz C GG Present A C TT G A A A Future • Nanotechnology is an enabling technology that will impact electronics and computing, materials and manufacturing, energy, transportation….

The double rings can be induced to self-assemble into nanotubes. Extremophile Proteins for Nano-scale Substrate Patterning Nano-scale engineering for high resolution lithography Future: Bio-based lithography •Batch self-assembly •Evolving •Inexpensive “quantum dots” nm resolution The Concept • • • • Nanopore in membrane (~2nm diameter) DNA in buffer Voltage clamp Measure current G. Church, Branton D. , J. Golovchenko , Harvard D. Deamer, UC Santa Cruz C GG Present A C TT G A A A Future • Nanotechnology is an enabling technology that will impact electronics and computing, materials and manufacturing, energy, transportation….

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An Overview Of Recent Developments In Nanotechnology by Meyyappan M.


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